TB-500
TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4. It plays a key role in tissue repair by promoting cell migration, blood vessel formation, and reducing inflammation. TB-500 is particularly effective for muscle, tendon, and ligament injuries, and is known for its systemic healing properties — meaning it can reach injured areas throughout the body regardless of injection site.
Frequency
Twice per week
Cycle Length
6-8 weeks loading, then as needed for maintenance
Route
Subcutaneous
Research Level
Established
Goals
Dosing Protocol
2.5-5 mg per injection (50-100 units), twice per week. Works in synergy with BPC-157. With standard reconstitution (5 mg in 1 mL), 0.05 mg per unit — 50 units = 2.5 mg, 100 units = 5 mg (full syringe) on a U-100 insulin syringe.
Reconstitution
Add 1 mL bacteriostatic water to a 5 mg vial.
Timing
Can be taken any time of day. Injection site does not need to be near the injury.
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Potential Side Effects
- Head rush shortly after injection
- Temporary lethargy
- Mild irritation at injection site
Important Warnings
- Not FDA-approved
- WADA-prohibited substance
- Theoretical concern about promoting existing tumor growth — avoid with active cancer
Works Well With
Research References
- Goldstein AL, et al. Expert Opin Biol Ther. 2012;12(S1):S37-S51. doi:10.1517/14712598.2012.697150
- Philp D, et al. FASEB J. 2004;18(2):405-407. doi:10.1096/fj.03-0510fje
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Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. TB-500 may be regulated differently in various jurisdictions. Always consult with a qualified healthcare provider before beginning any peptide protocol. PepStack Pro does not sell peptides or provide medical advice. Content reviewed by Dr. Seth Miller, MD.